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Tобрекс-Я не врач, но думаю, что это нужно знать всем.

Tobramycin has caused kidney problems, nerve damage, or permanent hearing loss, even at usual doses. Hearing loss can occur even after the medicine is stopped. If you already have kidney problems or hearing difficulty, tell your doctor. Notify your doctor right away if any of the following occur: ringing in ears, hearing loss, unusual change in amount of urine, dizziness, numbness, skin tingling, muscle twitching, or seizures. Tobramycin may be stopped if you develop kidney or hearing problems. Your doctor will monitor your progress to minimize the possibility of these effects occurring and to run certain tests (eg, hearing and/or kidney tests). Do not use Tobramycin with other medicines that can cause nerve, kidney, or hearing problems. Other factors that increase the risk of these side effects occurring include premature and newborn infants, advanced age, or dehydration. Avoid other medicines that may harm the kidneys or decrease hearing (eg, other aminoglycosides [eg, gentamicin], cephaloridine, viomycin, polymyxin B, colistin, cisplatin, vancomycin) while you are using Tobramycin. Do not use Tobramycin with certain diuretics (eg, furosemide, ethacrynic acid).

Tobramycin may cause fetal harm if used during pregnancy.

Read more: http://www.drugs.com/cdi/tobramycin.html#ixzz0ubfhz9Lu